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Silencing cholera's 'social media'
ScienceDaily (24 May 2016)
Bacteria use a form of 'social media' communication, quorum sensing, to monitor how many of their species are in the neighborhood. This is important in the pathogenicity of Vibrio cholerae, the cause of cholera. In a new study scientists explore the molecular mechanism whereby the quorum sensing response regulator LuxO regulates V. cholerae's pathogenicity.
Suivre les téléphones pour étudier l'expansion du choléra
Ecole polytechnique fédérale de Lausanne (24 mai 2016)
Pour la première fois, des chercheurs de l’EPFL ont utilisé des relevés de téléphones mobiles pour reconstituer l’expansion d’une épidémie de choléra.
Temperature Influences Gene Expression, Life Cycle in Vibrio cholerae
American Society for Microbiology (20 May 2016)
Vibrio cholerae infects roughly four million people annually, worldwide, causing severe diarrheal disease, and killing an estimated 140,000 people. Its success as a pathogen belies the challenges this bacterium faces. The waters this bacterium inhabits when it’s not infecting H. sapiens can be 40 degrees Fahrenheit cooler than our normal body temperature. Now a team of investigators from the University of California, Santa Cruz provides new insights into...
Single-dose inactivated cholera vaccine regimen shows efficacy in Bangladesh
2 Minute Medicine (6 May 2016)
...In this randomized, placebo controlled trial, a single-dose regimen of inactivated cholera vaccine was linked with 40% vaccine efficacy against all cholera episodes and 63% vaccine efficacy against severely dehydrating cholera episodes among nonpregnant residents of Dhaka, Bangladesh over 6 months.